Quality level: 200
Colour: white to off-white
Solubility: acetic acid: water: soluble, transparent, colorless
Action mode: protein synthesis | interferes
The spectrum of antibiotic activity: mushrooms
Sent in: dry ice
Storage temperature: −20 ° C
Cl [H] .CN (CC [C @@ H] (N) CC (= O) N [C @ H] 1C = C [C @@ H] (O [C @@ H] 1C (O) = O) N2C = CC (N) = NC2 = O) C (N) = N
Blasticidin S belongs to the class of aminoacylnucleoside antibiotics. Inhibits protein synthesis in bacteria and eukaryotes. It also has fungicidal properties and prevents rice blast disease.
Chemical structure: nucleoside
Blasticidin S is used as a selection agent for transformed cells containing the bls, bsr, or BSD resistance genes. Blasticidin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells. It is also used to study protein synthesis at the level of peptide bond formation.
Biochemical / Physiological Actions
Blasticidin S inhibits release factor-induced peptidyl-tRNA hydrolysis. It enhances the binding of tRNA to the large ribosome subunit and to some extent inhibits the formation of peptide bonds.
Bottomless glass bottle. The content is within the inserted fused cone.
Keep the container tightly closed in a dry and well-ventilated place. Store in a dry place. Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / highly toxic hazardous materials