pBridge plsamid

Properties

Form: dust

Quality level: 200

Colour: white to off-white

Solubility: acetic acid: water: soluble, transparent, colorless

Featured Industry

farming
Environmental

Action mode: protein synthesis | interferes

The spectrum of antibiotic activity: mushrooms

Sent in: dry ice

Storage temperature: −20 ° C

SMILES chain

Cl [H] .CN (CC [C @@ H] (N) CC (= O) N [C @ H] 1C = C [C @@ H] (O [C @@ H] 1C (O) = O) N2C = CC (N) = NC2 = O) C (N) = N

General description

Blasticidin S belongs to the class of aminoacylnucleoside antibiotics. Inhibits protein synthesis in bacteria and eukaryotes. It also has fungicidal properties and prevents rice blast disease.
Chemical structure: nucleoside

Request

Blasticidin S is used as a selection agent for transformed cells containing the bls, bsr, or BSD resistance genes. Blasticidin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells. It is also used to study protein synthesis at the level of peptide bond formation.

Biochemical / Physiological Actions

Blasticidin S inhibits release factor-induced peptidyl-tRNA hydrolysis. It enhances the binding of tRNA to the large ribosome subunit and to some extent inhibits the formation of peptide bonds.

Packaging

Bottomless glass bottle. The content is within the inserted fused cone.

Other notes

Keep the container tightly closed in a dry and well-ventilated place. Store in a dry place. Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / highly toxic hazardous materials

Leave a Reply

Your email address will not be published.